The likelihood ratio test demonstrated that each blood biomarker added a significant contribution to the NAC disease stage (anemia: χ2=16.92, P<0.001; hyperbilirubinemia: χ2=28.78, P<0.001; high urea: χ2=18.29, P<0.001; hypoalbuminemia: χ2=16.12, P<0.001; high ALP: χ2=26.81, P<0.001; high CRP: χ2=19.93, P<0.001; hyponatremia: χ2=15.62, P<0.001; troponin‐T >56 ng/L: χ2=88.67, P<0.001) (Figure 2). The gene discussed is CRP; the disease is Hyponatremia.