REN and fibrosis: IgAN: IgA nephropathy; RAASi: Renin-angiotensin-aldosterone system inhibitors; UPCR: Urine protein/creatinine ratio; TG: Triglycerides; TC: Total cholesterol; eGFR: Estimated glomerular filtration rate; SCr: Serum creatinine; M: Mesangial hypercellularity; E: Endocapillary cellularity; S: Segmental sclerosis; T: Interstitial fibrosis/tubular atrophy; C: Crescents; n: Number.