Anti-tumour necrosis factor (anti-TNF)-α agents have been associated with a broad range of infections, including tuberculosis and opportunistic infections.10 It is recommended that all patients undergo screening for Hepatitis B and well as tuberculosis before starting this class of medication, as both can be reactivated after treatment initiation.11 A positive tuberculosis QuantiFERON test necessitates a chest radiograph to rule out active infection. This evidence concerns the gene TNF and infection.