In addition, Luo et al. conducted a functional network analysis of differentially expressed miRNAs and mRNAs between sex-linked dwarf chickens and normal chickens and found that let-7b and miR-128 may play a key role in GHR deficiency-induced muscle mass loss through the MAPK pathway (Luo et al., 2016). This evidence concerns the gene GHR and hyperinsulinemic hypoglycemia, familial, 4.