For example, breast cancer cells may secrete cytokines such as interleukin-6 (IL-6) and interleukin-8 (IL-8) which trigger signaling pathways involved in immune evasion, cell proliferation, angiogenesis, breast cancer chemoresistance, and epithelial-mesenchymal transition (EMT) [2]. This evidence concerns the gene IL6 and breast carcinoma.