↓ The expression of IL6, IL1B, and ACTA2 mRNA in the liver; ↓ levels of serum alanine aminotransferase; ↓ MASH; ↓ tumor diameter; ↑ intestinal microbiome, the genera Blautia and Ruminococcus; ↓ Dorea and Erysipelotrichaceae. The gene discussed is ACTA2; the disease is neoplasm.