↓ Hepatic pathological changes; ↓ incidence and multiplicity of the tumor; ↑ liver functions; ↓ hepatic inflammation; ↓ NF-κB p65; ↓ TNF-α, MCP-1, iNOS, COX-2, NF-κB, and MMP-9; ↓ activation of the MAPK/Akt. The gene discussed is MMP9; the disease is neoplasm.