↓ Steatosis, fibrosis associated with decreasing serum aminotransferases; ↓ IFNγ, IL-1β, and IFNγ-inducible protein 10; ↓ VEGF, glypican-3, and prothrombin; ↑ Nrf2; ↓ hepatic C/EBPβ, CYP2E1, p-ERK1/2, and p67phox; ↓ SREBP1c. The gene discussed is MAPK3; the disease is steatosis.