Genetic deficiency is an important causal factor (Sudhakar et al., 2021), and several genes have been reported to be responsible for AT, including those in the cilia and flagellum-associated protein (CFAP) family, the coiled-coil domain-containing family, and the dynein axonemal heavy chain (DNAH) family (Sha et al., 2019; Tu et al., 2019; Wang et al., 2019; Chen et al., 2021; Zhang et al., 2022; Zhuang et al., 2022). The gene discussed is DNAH3; the disease is ataxia telangiectasia.