Indeed, there is a growing body of work suggesting that dysregulation of the NRG1 type III/ERBB2/3 signaling in Schwann cells isa common pathogenic mechanism for several demyelinating CMT subtypes (El-Bazzal et al., 2023; Jiang et al., 2022; Lee et al., 2017). The gene discussed is ERBB2; the disease is Charcot-Marie-Tooth disease.