LCDR and cancer: For instance, while the lncRNA c-Myc-inducible long noncoding RNA inactivating p53 (MILIP) represses the tumor suppressor p53 and promotes tumorigenesis in diverse cancer types including LUAD [30], the lncRNA lysosome cell death regulator (LCDR) regulates the integrity of lysosomal membrane and promote LUAD cell survival [31].