We examined chemokine receptor expression of IgG+plasma cells in obese tumor samples and non-obese tumor samples, including CXCR3, CXCR4 and CXCR5, and found that IgG+plasma cells in obese CRC highly expressed CXCR4 (Fig. 5C). The gene discussed is CXCR5; the disease is colorectal carcinoma.