FKNKO mice that received rAAV–mFKN (2376 ± 1339) and rAAV–sFKN (2470 ± 1325) then subjected to sustained 10 weeks of diabetes (10-wk D) showed significantly higher FKN levels compared to WT mice (Student’s t test p < 0.05). This evidence concerns the gene CX3CL1 and diabetes mellitus.