In recent years, there has been an increasing number of reports of positive anti-SSA antibodies in patients diagnosed with TAFRO; in a previous report, all Sjögren syndrome (SS) patients with TAFRO-like symptoms were positive for anti-SSA antibodies7, whereas in other studies, some patients with positive anti-SSA antibodies did not have SS8,9. The gene discussed is TRIM21; the disease is synovial sarcoma.