ZC3H12A and metabolic dysfunction-associated steatohepatitis: In addition, bioinformatic analysis revealed that in the cohort of NASH patients analyzed by Govaere et al,20 divided according to fibrosis stage, ZC3H12A expression was significantly induced in the livers of patients from the F3 and F4 groups compared with those of the normal liver and F0–F1 groups (Figure 1D).