For instance, three of the KEGG pathways—“CYTOSOLIC DNA SENSING PATHWAY,” “ANTIGEN PROCESSING AND PRESENTATION”, and “OLFACTORY TRANSDUCTION”—were simultaneously enriched in BRCA, COAD, ESCA, indicating that HMGN1 could exhibit a few common biological effects or employ similar mechanism in the above 3 types of cancers. The gene discussed is HMGN1; the disease is cancer.