Furthermore, T cell checkpoint dysregulation may play a part in the pathogenesis of GCA, as a higher expression of programmed cell death receptor-1 (PD-1) on T cells and lower expression of programmed death ligand-1 (PD-L1) on dendritic cells (DCs) have been reported in temporal artery biopsies (TABs) from GCA patients [10]. The gene discussed is CD274; the disease is temporal arteritis.