Specifically, an elevated ApoB/ApoA1 ratio demonstrated a positive association with the occurrence rate of TIA (IVW, odds ratio (OR) = 1.180, 95% confidence interval (CI) = 1.088,1.280, PFDR=1.553e-04; MR-PRESSO, PFDR=4.233e-04) (Fig. 2, Additional file, Table S5, Figure S1). This evidence concerns the gene APOA1 and transient ischemic attack.