GPT and gastrointestinal disease: As shown in Table 2, we identified 13 baseline factors that were potentially associated with lower BMD response (P < 0.10): gastrointestinal disease, prior bisphosphonate or glucocorticoid treatment, no vitamin K2 supplementation, low serum 25(OH)D level, low serum PINP level, unhealthy lifestyle (including excessive smoking, tea, coffee, and drinking), vegetarian diet pattern, low ALT level, and high BMD at baseline.