Ranking by the q-value, the other 17 pathways, i.e. oxidative phosphorylation, AGE-RAGE signaling pathway in diabetic complications, amoebiasis, parkinson’s disease, platelet activation, axon guidance, cardiac muscle contraction, fatty acid degradation, Alzheimer’s disease, arachidonic acid metabolism, basal cell carcinoma, TGF-beta signaling pathway, Huntington’s disease, proteasome, malaria, vascular smooth muscle contraction, were also included in the top-20 most enriched pathways. This evidence concerns the gene RENBP and early-onset autosomal dominant Alzheimer disease.