The incidence and course of ROP are thought to be influenced by other risk factors, including anemia, sepsis, postnatal weight gain, serum levels of insulin-like growth factor-1 (IGF-1), thrombocytopenia, bilirubin level, gender, multiple gestations, intraventricular hemorrhage, and blood transfusion [4]. The gene discussed is IGF1; the disease is Sepsis.