In a recent study, HLA typing of 26 patients with GFAP autoimmunity did not reveal significant differences in carrier frequencies between patients and controls for class I (A, B, C) and class II (DRB1, DQB1, DQA1, and DPB1) genes [13], however in dogs anti-GFAP meningoencephalomyelitis is limited to specific breeds [3, 14, 15, 32, 35, 37] what likely supports the existence of some genetic susceptibility factors. This evidence concerns the gene HLA-DPB1 and Autoimmunity.