ANKRD1 and cancer: A positive correlation was found in lung (LUSC), cervical (CESC) and head/neck (HNSC) SCCs of the TCGA database (https://portal.gdc.cancer.gov/) between levels of ANKRD1 expression and the mesenchymal ANKRD1-dependent gene signature that we established (Fig. 4g), which, by the EPIC (Estimating the Proportions of Immune and Cancer cells41) tool, was strongly associated with the estimated proportion of CAFs in tumors (Supplementary Fig. 3f).