TYR and Erythema: In adults and adolescents, the underlying erythema is barely visible and there is hypopigmentation in the classic areas of involvement,36 possibly due to the inhibition of tyrosinase function in melanocytes by Malassezia metabolites, with less pigment production.37, 38 Black children often present with erythema, desquamation and hypopigmentation of the affected areas and overlying AD, which accentuates the hypopigmentation.37, 39