These results are supported by the literature, such that DA affected the TRXR1 gene and protein expressions in lung cancer (A549) and breast cancer (MCF-7 and MDA-MB-453) cell lines, but the actual effect was observed on DA acid has cytotoxic, antimigratory, apoptotic, and necrotic activity in hepatocellular carcinoma (HepG2) cells in vitro. The gene discussed is TXNRD1; the disease is lung cancer.