Genes in cluster 8 (GSTO2, LRRC34), 9 (CLPTM1L) and 10 (CTSS, SETDB1, ANXA9, GOLPH3L, HORMAD1, PPIL3, CASP9, ALS2CR12) underlie the association between melanoma and cancers. This evidence concerns the gene SETDB1 and cancer.