TP53 and neoplasm: Genomic DNA was isolated from blood and biopsies and submitted to massive parallel sequencing of BRCA1, BRCA2, and TP53 genes, resulting in average depth coverage for tumor samples of 2,330,744 reads for BRCA1 (range: 442,640–7,475,773), 1,965,145 reads for BRCA2 (range: 227,065–5,377,818), and 1,505,640 reads for TP53 (range: 961,945–2,375,777).