Have evidence that proinflammatory cytokines (e.g., TNF-α, IL-1, and IL-6), and chemokines (e.g., CC-chemokine ligand 2 (CCL2), CC-chemokine ligand 5 (CCL5), and chemokines chemokine (C-X-C motif) ligand 8 (CXCL8)) are transcriptional targets of NFAT5 in stroke [187]. This evidence concerns the gene CXCL8 and stroke disorder.