HMGB1 and neoplasm: These DAMPs encompass cell surface exposure of CRT, heat‐shock proteins (HSP70 and HSP90), and high‐mobility group box‐1 (HMGB1).[18] To determine whether Mn‐N/C treatment triggers ICD of tumor cells in vivo, we sorted out the tumor cells (RFP+) from MC38 tumor‐bearing mice and analyzed the expression of ICD markers including Cxcl10, Hmgb1, and Ddit3.