To further confirm that CSN6‐mediated tumor growth is YAP1‐dependent, we overexpressed YAP1‐5SA, a constitutive‐active YAP1, and found that YAP1‐5SA can rescue CSN6 KD‐mediated YAP1 target gene suppression, colony formation inhibition, and transcriptional attenuation (Figure 2K–M). This evidence concerns the gene COPS6 and neoplasm.