Importantly, the combination of verteporfin and AAV‐shHMGCS1 treatment was more efficient in hindering tumor growth than verteporfin or AAV‐shHMGCS1 alone in CSN6/HMGCS1 high PDX as demonstrated by reduced tumor volume (Figure 8A) and reduced tumor weight (Figure 8B,C). The gene discussed is HMGCS1; the disease is neoplasm.