PLP1 and cancer: A meticulous exploration of the implicated biological processes and molecular mechanisms governing cancer development is imperative for comprehensive understanding and warrants further investigation.To conclude, combining our comprehensive bioinformatics analysis with scientific research experiments, our study enabled the identification of four candidates for potential prognostic value of BC and found out the tip of the iceberg function of CDH19, PLP1, TRIB3, and RELN. Our finding pointed to a few research orientations for those proteins in BC.