In this study, the expression levels of 15 MRDEGs (SLC11A1, SPP1, CXCL9, MMP3, CXCL8, CIITA, C5AR1, WNT5A, PDGFRA, FABP4, TIMP1, CCL22, CTSD, ADAM8, MS4A1) were analyzed in two groups of colon cancer patients with high/low scores in both TCGA-COADREAD (Fig. 6A) and GEO datasets (Fig. 6B). This evidence concerns the gene TIMP1 and colonic neoplasm.