Although there is a relative paucity of high-quality immunohistochemistry reagents for the detection of GPRC5D protein in normal (non-diseased) and tumor tissues, GPRC5D expression profiling can be accomplished by augmenting immunohistochemical data with complementary assays, such as in situ hybridization (ISH), RNA-sequencing, and flow cytometry [19, 20, 24, 25]. Here, GPRC5D is linked to neoplasm.