Consistent with the subcutaneous model, we found a significant increase in the infiltration of macrophages, monocytes, and neutrophils (Fig. 2l), whereas a decreased infiltration of DCs, B cells, CD4+ T, and CD8+ T cells in RNase1-overexpressing tumor (Fig. 2l,, m), by comparing the cell number of each subpopulation of immune subsets in control tumors. This evidence concerns the gene RNASE1 and neoplasm.