Concerning the involvement of this transcription factor in fibrogenesis, recent data indicate that alveolar accumulation of C/EBP-β in lung macrophages from patients and mice with pulmonary fibrosis causes upregulation of several profibrotic factors promoting pulmonary fibrosis, while its pharmacological degradation determines an effective therapeutic response against experimental fibrosis [37]. Here, CEBPB is linked to pulmonary fibrosis.