Moreover, in the milieu of gastric cancer – a disease marked by pronounced heterogeneity and a strong inflammatory component – there is a noted alteration in the expression and regulatory dynamics of these markers.[31] Typically, the levels of E-selectin, MCP-1, tissue factor, IL-6R, and FABP4 are elevated in gastric cancer tissues, with their aberrant expression closely tied to tumor proliferation, invasion, metastasis, and overall patient prognosis. This evidence concerns the gene IL6R and neoplasm.