SERPINE1 and atherosclerosis: Endothelial-to-Mesenchymal Transition, implicated in diseases like fibrosis and atherosclerosis, is a potential therapeutic target.[24] Prior research highlights differences in endothelial marker expression after radiation, complicating the understanding of radiation-induced vascular changes.[25] Increased ICAM-1, E-selectin, and PAI-1 align with our findings, emphasizing their importance in early vascular damage.