SELP and meningioma: In AVM, strong ICAM-1 expression suggests an inflammatory-driven pathology,[27–29] whereas glial tumors exhibit low IHC expression and the absence of P-selectin, indicating minimal prothrombotic involvement.[6,27,29–31] Meningioma and metastasis groups, with varied IHC expressions, suggest a lower likelihood of thrombotic events but a consistent inflammatory pathogenesis.[27]