Associations of non-HLA genes with sIgAD have been also demonstrated, although the particular variants of these genes were associated in parallel with autoimmune diseases like type 1 diabetes (T1D) and systemic lupus erythematosus (SLE)—Interferon Induced With Helicase C Domain 1 (IFIH1) or T1D and multiple sclerosis—C-Type Lectin Domain Containing 16A (CLEC16A). The gene discussed is CLEC16A; the disease is type 1 diabetes mellitus.