In a newly diagnosed glioblastoma (World Health Organization [WHO] grade IV, isocitrate dehydrogenase [IDH] wild-type), [18F]BBPA histogram separated the central necrosis (skewness 1.019, tendency 0.064) from the ring-like proliferating tumors (skewness 0.191, tendency 0.013), whom metabolic characteristics was suggestive of glioblastoma. This evidence concerns the gene IDH3A and glioblastoma.