In the p160 family, the SRC-1 (AUC 0.66 [95% CI 0.548–0.774]; Fig. 1F), the SRC-2 (AUC 0.70 [95% CI 0.611–0.805]; Fig. 1G), and the SRC-3 (AUC 0.72 [95% CI 0.609–0.845]; Fig. 1H) genes had a significant prediction of PCa. Here, NCOA3 is linked to posterior cortical atrophy.