Literature review and database analysis to further understand the mechanism underlying this regulation, revealed the role of WNT1 as a stimulator within the WNT/β-catenin signaling pathway [16, 17], while some investigations indicate that WNT1 accelerates the course of growth and metastasis in gastric carcinoma cell through transcriptional activation [11]. The gene discussed is WNT1; the disease is gastric carcinoma.