ACOD1 and Sepsis: To achieve this, we subjected 8–10 weeks old male C57BL/6NJ (WT) and C57BL/6NJ-Acod1em1(IMPC)J/J (Acod1 KO) to sepsis via cecal slurry injection for 24 hr as previously described (Gong and Wen, 2019).