CHI3L1 and hepatocellular carcinoma: Compared with that in the healthy controls (median: 32.70 ng/mL, P=0.001) and patients with CHB without HCC (median: 38.72 ng/mL, P=0.001), the CHI3L1 concentrations were significantly higher in patients with CHB and HCC (median: 122.14 ng/mL, P=0.001, Figure 2(a)).