(1) ATRX loss or TP53 mutation astrocytoma;(2) ATRX loss or TP53 mutation or anaplastic features or high mitotic index astrocytoma;ATRX loss or TP53 mutation or CDKN2A/2B homozygous deletion or CDKN2A/B astrocytom;Pilocytic astrocytoma. This evidence concerns the gene CDKN2A and pilocytic astrocytoma.