Previous studies have found that the synthesis of the compound Derivative 3-[(decahydronaphthalen-6-yl)methyl]-2,5-dihydroxycyclohexa-2,5-diene-1,4-dione (RF-Id) inhibits IAP family proteins and the NFκB pathway, inducing apoptosis in GBM cells. The gene discussed is NFKB1; the disease is glioblastoma.