Type 1 diabetes mellitus (T1DM) occurs due to autoimmunity against the beta cells of the pancreas that are involved in the formation of insulin, which results in insulin deficiency, whereas impaired insulin secretion, varying degrees of insulin resistance, and enhanced hepatic glucose production are the salient features of type 2 diabetes mellitus (T2DM) [1]. This evidence concerns the gene INS and type 1 diabetes mellitus.