Among central nodes were ERBB2 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2), CRK (Cysteine-rich receptor-like-kinase), HRAS, and KRAS (Kirsten rat sarcoma virus), all of which were proto-oncogenes involved in the development of various cancer types. Here, KRAS is linked to cancer.