IGHE and anemia (phenotype): Besides low vitamin D levels in 14/24 (58%) patients (range 7–29 ng/ml), the most frequent laboratory findings were elevated antinuclear antibodies (ANA) present in 14/25 (56%) (range 1:100–1:800), elevated IgE in 7/25 (28%) and mild anemia in 4/25 (16%) cases.