Furthermore, high baseline IL-6 levels (HR 2.146, 95%CI 1.361-3.383, p=0.001), high CRP levels (HR 1.846, 95%CI 1.128-3.022, p=0.015), non-O blood type (HR 0.523, 95%CI 0.346-0.789, p=0.002), cirrhosis (HR 1.499, 95%CI 1.012-2.220, p=0.043), and high AFP (HR 2.490, 95%CI 1.607-3.859, p<0.001) were still found to be significant factors associated with poor OS (Table 6). This evidence concerns the gene IL6 and Cirrhosis.