So, in line with the clinical data obtained from NHL patients, assessment of NHL cells was conducted in biopsy specimens by fluorescence microscopy which revealed that the increased intensity of MDR marker Pgp and MRP1 in non-responder group in post-chemotherapy phase compared to pre-chemo group (here, post-chemo non-responder groups are the follow up patients of pre-chemo groups), which was strongly associated with the worse treatment outcome (Figure 2C). The gene discussed is PGP; the disease is non-Hodgkin lymphoma.