IFNA17 and neoplasm: Meanwhile, the GSEA analyses of the DEGs comparing the groups between high and low E3PMP scores showed that cancer promoting pathways such as E2F, G2M checkpoint, INF-α, mTORC1 and cell cycle signals were significantly up-regulated, while tumor suppressor pathways such as primary immune response, chemokine receptor and immune rejection were significantly down-regulated (Figures 3C, D).