Although we observed no upregulation of Vgfa in endothelial cells of YUMM3.3 tumors, INHBA overexpression also promotes tumor vascularization in B16-F1 melanoma and in transgenic mouse models of skin squamous cell carcinoma, where this effect was enhanced by a polarizing effect on tumor-associated macrophages (16, 19). Here, INHBA is linked to skin squamous cell carcinoma.