Multivariate analysis demonstrated that tumor stage (HR 3.089, 95% CI [1.785–5.346], P < 0.001), smoking (HR 1.820, 95% CI [1.021–3.244], P = 0.042) and high DJ-1 (HR 5.298, 95% CI [2.697–10.406], P < 0.001) were independent prognostic factors of PFS. This evidence concerns the gene PARK7 and neoplasm.